TwittIRC - the way Twitter was meant to be
I was talking a bit about Isaac, my smallish DSL for writing IRC bots in Ruby. I wrote it so I could create a Twitter IRC gateway. The result is TwittIRC which has been my preferred Twitter client the last couple of days. There are still some quirks and annoyances, but in general it fits me very, very, very well. Grab the source or use my TwittIRC bot at freenode if you dare.